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Anti-icos Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human icos Antibody MOM-18383 1mg Please Inquiry
Product Detail
Cat
MOM-18383
Product Overview
Recombinant Mouse Antibody is specific to Human ICOS, expressed in Chinese Hamster Ovary cells(CHO)
Target
ICOS
Type
IgG
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in ELISA, FC, IP, FuncS, IF, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
Gene ID
29851
Synonyms
ICOS; inducible T-cell co-stimulator; inducible T-cell costimulator; activation inducible lymphocyte immunomediatory molecule; AILIM; CD278; inducible costimulator; activation-inducible lymphocyte immunomediatory molecule; CVID1; MGC39850
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