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Anti-il12rb1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human il12rb1 Antibody Fab Fragment MOM-18386-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18386-F(P)
Product Overview
Recombinant Mouse Antibody Fab Fragment is against Human IL12RB1, expressed in E. coli
Target
IL12RB1
Type
Fab
Immunogen
Recombinant fragment corresponding to the extracellular domain of Human IL12RB1.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Function
cytokine receptor activity; contributes_to interleukin-12 receptor activity; contributes_to interleukin-12 receptor binding; contributes_to interleukin-23 binding; contributes_to interleukin-23 receptor activity; receptor activity;
Gene ID
3594
Synonyms
IL12RB1; interleukin 12 receptor, beta 1; IL12RB; interleukin-12 receptor subunit beta-1; CD212; IL-12RB1; IL-12R-beta-1; IL-12R subunit beta-1; IL-12 receptor beta component; IL-12 receptor subunit beta-1; interleukin-12 receptor beta-1 chain; IL-12R-BETA1; MGC34454
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