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Anti-il12rb1 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human il12rb1 Antibody MOM-18386 1mg Please Inquiry
Product Detail
Cat
MOM-18386
Product Overview
Recombinant Mouse Antibody is specific to Human IL12RB1, expressed in Chinese Hamster Ovary cells(CHO)
Target
IL12RB1
Type
IgG
Immunogen
Recombinant fragment corresponding to the extracellular domain of Human IL12RB1.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by analysis by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Background
Antigen Description
Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Function
cytokine receptor activity; contributes_to interleukin-12 receptor activity; contributes_to interleukin-12 receptor binding; contributes_to interleukin-23 binding; contributes_to interleukin-23 receptor activity; receptor activity;
Gene ID
3594
Synonyms
IL12RB1; interleukin 12 receptor, beta 1; IL12RB; interleukin-12 receptor subunit beta-1; CD212; IL-12RB1; IL-12R-beta-1; IL-12R subunit beta-1; IL-12 receptor beta component; IL-12 receptor subunit beta-1; interleukin-12 receptor beta-1 chain; IL-12R-BETA1; MGC34454
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