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Anti-il23r Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human il23r Antibody Fab Fragment MOM-18396-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18396-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment specifically binds to Human IL23R, expressed in Chinese Hamster Ovary cells(CHO)
Target
IL23R
Type
Fab
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95%, by SDS-PAGE with silver staining, under reducing conditions.
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Function
contributes_to interleukin-12 receptor binding; contributes_to interleukin-23 binding; contributes_to interleukin-23 receptor activity; receptor activity;
Gene ID
149233
Synonyms
IL23R; interleukin 23 receptor; interleukin-23 receptor; IL 23R; IL-23 receptor
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