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Anti-il4r Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human il4r Antibody Fab Fragment MOM-18402-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18402-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment is bind to Human IL4R, expressed in Chinese Hamster Ovary cells(CHO)
Target
IL4R
Type
Fab
Immunogen
Recombinant human interleukin 4 soluble receptor (IL-4sR) purified from the insect cell line Sf 21
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
At -20°C for one year.
Background
Antigen Description
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammmation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.Soluble IL4R (sIL4R) inhibits IL4-mediated cell proliferation and IL5 up-regulation by T-cells.
Function
insulin receptor substrate binding; interleukin-4 receptor activity; protein binding; receptor activity; receptor signaling protein activity;
Gene ID
3566
Synonyms
IL4R; interleukin 4 receptor; interleukin-4 receptor subunit alpha; CD124; IL-4 receptor subunit alpha; interleukin-4 receptor alpha chain; IL4RA; IL-4RA
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