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Anti-muc1 Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human muc1 Antibody Fab Fragment MOM-18065-F(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18065-F(P)
Product Overview
Recombinant Mouse Antibody Fab Fragment binds selectively to Human MUC1, expressed in E. coli
Target
MUC1
Type
Mouse IgG Fab
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H Chain: QVQLVQS; L Chain: DIQMTQS
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain which is involved in cell signaling, through phosphorylations and protein-protein interactions. Modulates signaling in ERK, SRC and NF-kappa-B pathways. In activated T-cells, influences directly or indirectly the Ras/MAPK pathway. Promotes tumor progression. Regulates TP53-mediated transcription and determines cell fate in the genotoxic stress response. Binds, together with KLF4, the PE21 promoter element of TP53 and represses TP53 activity.
Function
RNA polymerase II core promoter proximal region sequence-specific DNA binding; p53 binding; protein binding; transcription cofactor activity
Gene ID
4582
Synonyms
EMA; PEM; PUM; KL-6; MAM6; PEMT; CD227; H23AG; MUC-1; MUC-1/X; MUC1/ZD; MUC-1/SEC; Episialin; DF3; H23; Krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen;Breast carcinoma associated antigen DF3; CA15.3; CD227 antigen; Epithelial membrane antigen; Epithelial mucin tandem repeat sequence; H23 antigen; H23AG; KL 6; Krebs von den Lungen-6; Mucin 1 precursor; Mucin-1 subunit beta; Peanut reactive urinary mucin
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