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Anti-notch1 Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human notch1 Antibody scFv Fragment MOM-18596-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18596-S(P)
Product Overview
Recombinant Mouse Antibody scFv Fragment specifically binds to Human NOTCH1, expressed in E. coli
Target
NOTCH1
Type
scFv
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May be important for normal lymphocyte function.
Function
calcium ion binding; chromatin DNA binding; core promoter binding; protein binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Gene ID
4851
Synonyms
NOTCH1; notch 1; Notch (Drosophila) homolog 1 (translocation associated) , Notch homolog 1, translocation associated (Drosophila) , TAN1; neurogenic locus notch homolog protein 1; Notch homolog 1, translocation-associated; translocation-associated notch protein TAN-1; hN1; TAN1;
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