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Anti-notch3 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human notch3 Antibody MOM-18448 1mg Please Inquiry
Product Detail
Cat
MOM-18448
Product Overview
Recombinant Mouse Antibody is specific to Human NOTCH3, expressed in Chinese Hamster Ovary cells(CHO)
Target
NOTCH3
Type
IgG
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut, FuncS, ELISA, FC, ICC and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
Function
calcium ion binding; protein binding; receptor activity;
Gene ID
4854
Synonyms
NOTCH3; notch 3; CADASIL, Notch (Drosophila) homolog 3 , Notch homolog 3 (Drosophila); neurogenic locus notch homolog protein 3; CASIL; Notch homolog 3; CADASIL
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