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Anti-olr1 Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human olr1 Antibody MOM-18597 1mg Please Inquiry
Product Detail
Cat
MOM-18597
Product Overview
Recombinant Mouse Antibody is specific to Human OLR1, expressed in Chinese Hamster Ovary cells(CHO)
Target
OLR1
Type
IgG
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Background
Antigen Description
Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis.
Function
binding; low-density lipoprotein receptor activity; receptor activity; sugar binding;
Gene ID
4973
Synonyms
OLR1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidised low density lipoprotein (lectin like) receptor 1; oxidized low-density lipoprotein receptor 1; CLEC8A; LOX 1; SCARE1; hLOX-1; ox LDL receptor 1; lectin-type oxidized LDL receptor 1; scavenger receptor class E, member 1; C-type lectin domain family 8 member A; oxidized low-density lipoprotein receptor 1, soluble form; LOX1; LOXIN; SLOX1;
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