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Anti-psca Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human psca Antibody Fab Fragment MOM-18604-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18604-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment specifically binds to Human PSCA, expressed in Chinese Hamster Ovary cells(CHO)
Target
PSCA
Type
Fab
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
Gene ID
8000
Synonyms
PSCA; prostate stem cell antigen; PRO232;
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