Follow us on:
Dedication / Services
To provide 50000 services and products to global scientific research units every year

Anti-ptprj Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ptprj Antibody scFv Fragment MOM-18306-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18306-S(P)
Product Overview
Recombinant Mouse Antibody scFv Fragment is bind to Human PTPRJ, expressed in E. coli
Target
PTPRJ
Type
scFv
Immunogen
PHA stimulated Human PBMC
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.
Background
Antigen Description
Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of CTNND1, PDGFRB, MET, RET (variant MEN2A), KDR, LYN, SRC, MAPK1, MAPK3, EGFR, TJP1, OCLN, PIK3R1 and PIK3R2. Plays a role in cell adhesion, migration, proliferation and differentiation. Involved in vascular development. Regulator of macrophage adhesion and spreading. Positively affects cell-matrix adhesion. Positive regulator of platelet activation and thrombosis. Negative regulator of cell proliferation. Negative regulator of PDGF-stimulated cell migration; through dephosphorylation of PDGFR. Positive regulator of endothelial cell survival, as well as of VEGF-induced SRC and AKT activation; through KDR dephosphorylation. Negative regulator of EGFR signaling pathway; through EGFR dephosphorylation. Enhances the barrier function of epithelial junctions during reassembly. Negatively regulates T-cell receptor (TCR) signaling. Upon T-cell TCR activation, it is up-regulated and excluded from the immunological synapses, while upon T-cell-antigen presenting cells (APC) disengagement, it is no longer excluded and can dephosphorylate PLCG1 and LAT to down-regulate prolongation of signaling.
Function
beta-catenin binding; delta-catenin binding; gamma-catenin binding; hydrolase activity; mitogen-activated protein kinase binding; phosphatase activity; phosphatase activity; platelet-derived growth factor receptor binding; protein binding; protein kinase binding; protein tyrosine phosphatase activity; protein tyrosine phosphatase activity;
Gene ID
5795
Synonyms
PTPRJ; protein tyrosine phosphatase, receptor type, J; receptor-type tyrosine-protein phosphatase eta; CD148; DEP1; HPTPeta; DEP-1; R-PTP-J; HPTP eta; CD148 antigen; density-enhanced phosphatase 1; protein-tyrosine phosphatase eta; human density enhanced phosphatase-1; protein-tyrosine phosphatase receptor type J; susceptibility to colon cancer 1, mouse, homolog of; protein tyrosine phosphatase, receptor type, J polypeptide; SCC1; R-PTP-ETA
Download Datasheet:

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
Loading...
Contact Us

USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email: 

Europe
Tel: 44-207-097-1828


© 2007 - 2017 Creative-Biolabs All Rights Reserved