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Anti-rgma Antibody scFv (CAT#: MOM-18485-S(P))

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human rgma Antibody scFv Fragment MOM-18485-S(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody scFv Fragment is bind to Human RGMA, expressed in E. coli
  • Target
  • RGMA
  • Type
  • scFv
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in ELISA, WB, Neut and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

BACKGROUND

  • Antigen Description
  • The Repulsive Guidance Molecule (RGM) family of proteins function as BMP co-receptors. It is hypothesized that RGM family members increase the sensitivity of cells in which they are expressed to BMP stimulation, thereby allowing these cells to respond earlier or more robustly to a low level of BMP ligand. RGM family members are an important addition to the complex array of regulatory molecules which help to generate specificity and tightly coordinate cellular responses to BMP ligands. RGM-A and RGM-B (DRAGON) are expressed in a complementary manner in the central nervous system; whilst RGM-A mediates repulsive axonal guidance and neural tube closure, DRAGON contributes to neuronal cell adhesion through homophilic interactions. RGMa also binds to the receptor neogenin and functions as a cell survival factor.
  • Synonyms
  • RGMA; RGM domain family, member A; repulsive guidance molecule A; RGM

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