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Anti-rora Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human rora Antibody Fab Fragment MOM-18487-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18487-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment is bind to Human RORA, expressed in Chinese Hamster Ovary cells(CHO)
Target
RORA
Type
Fab
Immunogen
Recombinant fragment, corresponding to amino acids 136-236 of Human ROR alpha + beta + gamma
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by analysis by SDS-PAGE.
Storage
Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Background
Antigen Description
ROR alpha, beta and gamma are members of the NR1 subfamily of nuclear hormone receptors. They can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. ROR alpha binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. ROR beta is required for normal postnatal development of rod and cone photoreceptor cells.
Function
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; zinc ion binding;
Gene ID
6095
Synonyms
RORA; RAR-related orphan receptor A; nuclear receptor ROR-alpha; NR1F1; ROR1; ROR2; ROR3; RZRA; ROR-alpha; nuclear receptor RZR-alpha; transcription factor RZR-alpha; retinoid-related orphan receptor alpha; nuclear receptor subfamily 1 group F member 1; thyroid hormone nuclear receptor alpha variant 4; retinoic acid receptor-related orphan receptor alpha; RZR-ALPHA; MGC119326; MGC119329; DKFZp686M2414
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