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Anti-rora Antibody scFv

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human rora Antibody scFv Fragment MOM-18487-S(P) 1mg Please Inquiry
Product Detail
Cat
MOM-18487-S(P)
Product Overview
Recombinant Mouse Antibody scFv Fragment specifically binds to Human RORA, expressed in E. coli
Target
RORA
Type
scFv
Immunogen
Recombinant fragment, corresponding to amino acids 136-236 of Human ROR alpha + beta + gamma
Species Reactivity
Human
Expression Host
E. coli
Applications
Suitable for use in ELISA, WB, Neut and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
>95.0% as determined by analysis by RP-HPLC.
Storage
Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Background
Antigen Description
ROR alpha, beta and gamma are members of the NR1 subfamily of nuclear hormone receptors. They can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. ROR alpha binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. ROR beta is required for normal postnatal development of rod and cone photoreceptor cells.
Function
ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; zinc ion binding;
Gene ID
6095
Synonyms
RORA; RAR-related orphan receptor A; nuclear receptor ROR-alpha; NR1F1; ROR1; ROR2; ROR3; RZRA; ROR-alpha; nuclear receptor RZR-alpha; transcription factor RZR-alpha; retinoid-related orphan receptor alpha; nuclear receptor subfamily 1 group F member 1; thyroid hormone nuclear receptor alpha variant 4; retinoic acid receptor-related orphan receptor alpha; RZR-ALPHA; MGC119326; MGC119329; DKFZp686M2414
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