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Anti-tnf alpha Antibody

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human tnf alpha Antibody MOM-18034 1mg Please Inquiry
Product Detail
Cat
MOM-18034
Product Overview
Recombinant Humanized (from mouse) Antibody binds selectively to Human TNF alpha, expressed in Chinese Hamster Ovary cells(CHO)
Target
TNF alpha
Type
Humanized(from mouse) IgG1
Immunogen
The details of the immunogen for this antibody are not available.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
Specificity
Tested positive against native antigen.
Predicted N terminal
H chain: EVQLVES; L Chain: DIQMTQS
Purity
Purity >95% by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
Function
cytokine activity; identical protein binding; protease binding; protein binding; transcription regulatory region DNA binding; tumor necrosis factor receptor binding
Gene ID
7124
Synonyms
DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor; APC1 protein; Cachectin; tumor necrosis factor-alpha; TNF, macrophage-derived; Differentiation inducing factor; Macrophage cytotoxic factor ; MCF; Necrosin; TNFalpha; TNF Monocyte Derived; TNF Superfamily Member 2; TNF superfamily, member 2; TNF, monocyte derived; TNFA; Tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor; Tumor necrosis factor, soluble form; Tumour Necrosis Factor Alpha
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