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Anti-tnfrsf10a Antibody Fab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human tnfrsf10a Antibody Fab Fragment MOM-18344-F(E) 1mg Please Inquiry
Product Detail
Cat
MOM-18344-F(E)
Product Overview
Recombinant Mouse Antibody Fab Fragment is directed against Human TNFRSF10A, expressed in Chinese Hamster Ovary cells(CHO)
Target
TNFRSF10A
Type
Fab
Immunogen
Fusion protein (Human). Fusion protein containing the extracellular part of DR4 and the constant part of the heavy chain of the human IgG1.
Species Reactivity
Human
Expression Host
CHO
Applications
Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
Specificity
Tested positive against native antigen.
Purity
Purity >95% by SDS-PAGE.
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.
Background
Antigen Description
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.
Function
TRAIL binding; death receptor activity; protein binding; receptor activity; transcription factor binding;
Gene ID
8797
Synonyms
TNFRSF10A; tumor necrosis factor receptor superfamily, member 10a; tumor necrosis factor receptor superfamily member 10A; Apo2; CD261; DR4; TRAILR 1; TRAIL-R1; TRAIL receptor 1; death receptor 4; cytotoxic TRAIL receptor; TNF-related apoptosis-inducing ligand receptor 1; tumor necrosis factor receptor superfamily member 10a variant 2; APO2; TRAILR1; TRAILR-1; MGC9365
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