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Recombinant Anti-GDF2 Mab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Anti-Human GDF2 Monoclonal Antibody HOM-19230 1mg Please Inquiry
Product Detail
Cat
HOM-19230
Product Overview
Recombinant humanized antibody expressed in CHO binding to human GDF2.
Target
GDF2
Type
Human IgG
Species Reactivity
Human
Expression Host
CHO
Applications
ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.
Clone
Monoclonal
Molecular Weight
145.41 kDa
Purity
>95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.
Stability
Samples are stable for up to twelve months from date of receipt at - °C and are stable for six months at 4 °C.
Ship
2-8°C, BLUE ICE
Background
Antigen Description
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. The important functioning of BMP signals in physiology is emphasized by the multitude of roles for dysregulated BMP signalling in pathological processes. Cancerous disease often involves misregulation of the BMP signalling system. Absence of BMP signalling is, for instance, an important factor in the progression of colon cancer, and conversely, overactivation of BMP signalling following reflux-induced esophagitis provokes Barrett's esophagus and is thus instrumental in the development of adenocarcinoma in the proximal portion of the gastrointestinal tract.
Function
cytokine activity; growth factor activity; protein binding;
Gene ID
2658
Synonyms
GDF2; growth differentiation factor 2; growth/differentiation factor 2; BMP 9; BMP9; GDF-2; bone morphogenetic protein 9; BMP-9;
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