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Recombinant Anti-ILT3 Mab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Anti-Human ILT3 Monoclonal Antibody HOM-19363 1mg Please Inquiry
Product Detail
Cat
HOM-19363
Product Overview
Recombinant humanized antibody expressed in CHO binding to human ILT3.
Target
LILRB4
Type
Human IgG
Species Reactivity
Human
Expression Host
CHO
Applications
ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.
Clone
Monoclonal
Molecular Weight
145.41 kDa
Purity
>95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.
Stability
Samples are stable for up to twelve months from date of receipt at - °C and are stable for six months at 4 °C.
Ship
2-8°C, BLUE ICE
Background
Antigen Description
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function
antigen binding;protein binding;receptor activity;
Gene ID
11006
Synonyms
HM18; ILT3; LIR5; CD85K; LIR-5; LILRB5
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