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Recombinant Anti-OSCAR Mab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Anti-Human OSCAR Monoclonal Antibody HOM-19416 1mg Please Inquiry
Product Detail
Cat
HOM-19416
Product Overview
Recombinant humanized antibody expressed in CHO binding to human OSCAR.
Target
OSCAR
Type
Human IgG
Species Reactivity
Human
Expression Host
CHO
Applications
ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.
Clone
Monoclonal
Molecular Weight
145.41 kDa
Purity
>95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.
Stability
Samples are stable for up to twelve months from date of receipt at - °C and are stable for six months at 4 °C.
Ship
2-8°C, BLUE ICE
Background
Antigen Description
Osteoclast-associated immunoglobulin-like receptor is a protein that in humans is encoded by the OSCAR gene. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Function
receptor activity;
Gene ID
126014
Synonyms
OSCAR; osteoclast associated, immunoglobulin-like receptor; osteoclast-associated immunoglobulin-like receptor; PIgR-3; hOSCAR; poly-Ig receptor 3; osteoclast-associated receptor; polymeric immunoglobulin receptor 3; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; PIGR3; MGC33613;
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