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Recombinant Anti-SEMA4B Mab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Anti-Human SEMA4B Monoclonal Antibody HOM-19457 1mg Please Inquiry
Product Detail
Cat
HOM-19457
Product Overview
Recombinant humanized antibody expressed in CHO binding to human SEMA4B.
Target
SEMA4B
Type
Human IgG
Species Reactivity
Human
Expression Host
CHO
Applications
ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.
Clone
Monoclonal
Molecular Weight
145.41 kDa
Purity
>95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.
Stability
Samples are stable for up to twelve months from date of receipt at - °C and are stable for six months at 4 °C.
Ship
2-8°C, BLUE ICE
Background
Antigen Description
Semaphorins are a class of secreted and membrane proteins that act as axonal growth cone guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric receptor complexes. They are usually cues to deflect axons from inappropriate regions, especially important in neural system development. The major class of proteins that act as their receptors are called plexins. The main receptors for semaphorins are plexins, which have established roles in regulating Rho-family GTPases. Recent work shows that plexins can also influence R-Ras, which, in turn, can regulate integrins. Such regulation is probably a common feature of semaphorin signalling and contributes substantially to our understanding of semaphorin biology.

Every semaphorin is characterised by the expression of a specific region of about 500 amino acids called the sema domain.
Function
receptor activity;
Gene ID
10509
Synonyms
SEMA4B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; SEMAC; semaphorin-4B; KIAA1745; MGC131831; SemC; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B;
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