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Recombinant Anti-Tnk1 Mab

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Anti-Human Tnk1 Monoclonal Antibody HOM-19486 1mg Please Inquiry
Product Detail
Cat
HOM-19486
Product Overview
Recombinant humanized antibody expressed in CHO binding to human Tnk1.
Target
TNK1
Type
Human IgG
Species Reactivity
Human
Expression Host
CHO
Applications
ELISA, WB, IHC, FCM, IP, IF. Optimal dilutions/concentrations should be determined by the end user.
Clone
Monoclonal
Molecular Weight
145.41 kDa
Purity
>95.0% as determined by analysis by RP-HPLC & analysis by SDS-PAGE.
Storage
Store it under sterile conditions at -20 °C upon receiving. Recommend to pack the antibody into smaller quantities for optimal storage.
Stability
Samples are stable for up to twelve months from date of receipt at - °C and are stable for six months at 4 °C.
Ship
2-8°C, BLUE ICE
Background
Antigen Description
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Function
ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; protein tyrosine kinase activity; signal transducer activity;
Gene ID
8711
Synonyms
TNK1; tyrosine kinase, non-receptor, 1; non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1; MGC46193;
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