Follow us on:
Dedication / Services
To provide 50000 services and products to global scientific research units every year

Recombinant Human Betacellulin

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Betacellulin CRP0875 1mg Please Inquiry
Product Detail
Cat
CRP0875
Product Overview
Recombinant Human Betacellulin produced in E.coli is a single non-glycosylated polypeptide chain containing 80 amino acids and having a molecular mass of approximately 9.0KDa.
Specificity
Fully biologically active when compared to standard. The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is < 0.05 ng/ml, corresponding to a Specific Activity of >2.0×107 IU/mg.
Endotoxin
Less than 1EU/mg of rHuBTC as determined by LAL method.
Purity
>97% by SDS-PAGE and HPLC analyses.
Storage
This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
Background
Antigen Description
Betacellulin (BTC) is a new member of the EGF family of cytokines that is comprised of at least ten proteins including EGF, TGF-α, amphiregulin, HB-EGF, and the various heregulins. All of these cytokines are synthesized as transmembrane precursors and are characterized by the presence of one or more EGF structural units in their extracellular domain. The soluble forms of these cytokines are released by proteolytic cleavage. BTC, a heparin-binding protein, was originally isolated from the conditioned media of mouse pancreatic beta tumor cells as a 32 kDa glycoprotein composed of 80 amino acid residues. Human and mouse cDNAs encode BTC precursor proteins of 178 and 177 amino acid residues, respectively.
Function
epidermal growth factor receptor binding, growth factor activity.
Gene ID
685
Synonyms
OTTHUMP00000160600; Probetacellulin precursor; Probetacellulin
Download Datasheet:

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
Loading...
Contact Us

USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email: 

Europe
Tel: 44-207-048-3343


© 2007 - 2017 Creative-Biolabs All Rights Reserved