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Recombinant Human Eotaxin-2 /CCL24

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Eotaxin-2 /CCL24 CRP08110 1mg Please Inquiry
Product Detail
Cat
CRP08110
Product Overview
Recombinant Human Eotaxin-2/CCL24 produced in E. coli is a single, non-glycosylated polypeptide chain containing 78 amino acids and having a molecular mass of 8.8 kDa.
Endotoxin
Less than 1EU/mg of rHuEotaxin-2/CCL24 as determined by LAL method.
Purity
>97% by SDS-PAGE and HPLC analyses.
Storage
This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
Background
Antigen Description
Eotaxin, also named MPIF-2 and Ckβ6, is a novel CC chemokine recently identified. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation).
Function
chemokine activity
Gene ID
6369
Synonyms
Ckb-6; MPIF2; MPIF-2; SCYA24; chemokine (C-C motif) ligand 24; eotaxin-2;MPIF2; CCL24_HUMAN; C-C motif chemokine 24 [Precursor]; Small-inducible cytokine A24;Myeloid progenitor inhibitory factor 2; CK-beta-6;Eosinophil chemotactic protein 2;Eotaxin-2.
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