Recombinant Human Epidermal Growth Factor
|Recombinant Human Epidermal Growth Factor
- Product Overview
- Epidermal Growth Factor (EGF) is a polypeptide growth factor which stimulates the proliferation of a wide range of epidermal and epithelial cells. Human EGF is a 6.2 kDa protein containing 53 amino acid residues.
- The ED50, calculated by the dose-dependant proliferation of murine BALB/c 3T3 cells is less than 2 ng/ml, corresponding to a specific activity of 1.0 x 105 IU/ mg.
- Less than 0.3ng/ug (0.3IEU/ug) determined by LAL test.
- >95% as determined by SDS-PAGE and SEC-HPLC.
- Lyophilized rHuEGF although stable at room temperature for 3 weeks, should be stored desiccated below -18oC. Upon reconstitution rHuEGF should be stored at 4oC between 2-7 days and for future use below -18oC. For long-term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Aliquot to avoid repeated freeze-thaw cycles.
- It is recommended to reconstitute the lyophilized rHuEGF in sterile 18MΩ-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
PDB rendering based on 1ivo.
- Antigen Description
- Epidermal growth factor (EGF) is a small mitogenic protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. This protein shows both strong sequential and functional homology with human type-alpha transforming growth factor (hTGF alpha), which is a competitor for EGF receptor sites. EGF is a small 53 amino acid residue long protein that contains three disulfide briges.
- calcium ion binding; epidermal growth factor receptor activating ligand activity; growth factor activity; protein binding
- Gene ID
- HOMG4, URG, Urogastrone, Pro-epidermal growth factor;Pro-epidermal growth factor precursor; epidermal growth factor (beta-urogastrone)
- Download Datasheet:
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