Recombinant Human Glia Maturation Factor beta
|Recombinant Human Glia Maturation Factor beta
- Product Overview
- Recombinant Human Glia Maturation Factor beta produced in E.coli is a single non-glycosylated polypeptide chain containing 141 amino acids and having a molecular mass of approximately 16.5KDa.
- The biological activity was determined by the does-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors yielding an ED50 <0.5ng/ml.
- rHuGMF-β as determined by LAL method.
- >98% by SDS-PAGE and HPLC analyses.
- This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
- Antigen Description
- GMF-β, a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family. GMF-β appears to play a role in the differentiation, maintenance, and regeneration of the nervous system. It also supports the progression of certain auto-immune diseases, possibly through its ability to induce the production and secretion of various pro-inflammatory cytokines.
- actin binding, enzyme activator activity, growth factor activity, protein kinase inhibitor activity, signal transducer activity.
- Gene ID
- GMF; GMF-beta; Glia maturation factor beta; glia maturation factor; beta
- Download Datasheet:
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