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Recombinant Human Interferon-β1b

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Interferon-β1b CRP0889 1mg Please Inquiry
Product Detail
Cat
CRP0889
Product Overview
Recombinant Human Interferon-β1b produced in E.coli is a single non-glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of approximately 18.5 kDa.
Specificity
Fully biologically active when compared to standard. The specific activity as determined in a viral resistance assay is less then 0.03 ng/ml, corresponding to a specific activity of 4.0 x107IU/ mg.
Endotoxin
Less than 1EU/μg of rHuIFN-β1b as determined by LAL method.
Purity
>96% by SDS-PAGE and HPLC analyses.
Storage
This lyophilized preparation is stable for several weeks at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
Recombinant Human Interferon-β1b
PDB rendering based on 1au1. Available structures:1au1
Background
Antigen Description
Interferon-beta is one of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity. The synthesis of IFN-beta can be induced by common inducers of interferons, including viruses, double-stranded RNA, and micro-organisms. It is induced also by some cytokines such as TNF and IL-1.
Function
interferon-alpha/beta receptor binding
Gene ID
3456
Synonyms
interferon beta 1; fibroblast; IFNB; IFB, IFF; IFNB_HUMAN; Interferon beta [Precursor]; IFN-beta; Fibroblast interferon;MGC96956;IFNB.
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