Follow us on:
Dedication / Services
To provide 50000 services and products to global scientific research units every year

Recombinant Human Vascular endothelial growth factor 165

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Human Vascular endothelial growth factor 165 CRP08101 1mg Please Inquiry
Product Detail
Cat
CRP08101
Product Overview
Recombinant human VEGF165 produced in E.coli is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Specificity
Fully biologically active when compared to standard. Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml.
Endotoxin
Less than 1EU/mg of rHuVEGF165 as determined by LAL method.
Purity
>95% by SDS-PAGE and HPLC analyses.
Storage
This lyophilized preparation is stable at 2-8°C, but should be kept at -20°C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8°C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
Recombinant Human Vascular endothelial growth factor 165
PDB rendering based on 1bj1.
Background
Antigen Description
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product.
Function
cell surface binding;extracellular matrix binding;growth factor activity;growth factor activity;heparin binding;platelet-derived growth factor receptor binding;protein binding;protein homodimerization activity;vascular endothelial growth factor receptor binding.
Gene ID
7422
Synonyms
VPF; VEGF; VEGF-A; VEGFA;MGC70609; VEGFA_HUMAN; Vascular permeability factor; Vegf120; Vegf164; Vegf188; vascular endothelial growth factor A; MGC70609; Vascular endothelial growth factor A precursor; Vascular permeability factor
Download Datasheet:

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
Loading...
Contact Us

USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email: 

Europe
Tel: 44-207-048-3343


© 2007 - 2017 Creative-Biolabs All Rights Reserved