Follow us on:
Dedication / Services
To provide 50000 services and products to global scientific research units every year

Recombinant Murine Interleukin-4

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Murine Interleukin-4 CRP0836 1mg Please Inquiry
Product Detail
Cat
CRP0836
Product Overview
Recombinant murine IL-4 produced in E.coli is a 13.5kDa globular protein containing 120 amino acid residues.
Specificity
The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is 5 x 105IU/mg.
Endotoxin
Less than 0.1ng/ug (1 IEU/ug) determined by LAL test.
Purity
>95% as determined by SDS-PAGE.
Storage
Lyophilized protein is stable for a few weeks at room temperature, but best stored at -20oC. Reconstituted murine IL-4 should be stored in working aliquots at -20oC. Aliquot to avoid repeated freeze-thaw cycles.
Reconstitution
It is recommended to reconstitute the lyophilized rmIL-4 in sterile 18MΩ-H2O containing at least 0.1% human serum albumin or bovine serum albumin to prepare a stock solution of no less than 5μg/ml of the cytokine.
Recombinant Murine Interleukin-4
Crystal structure of human IL-4(2INT).
Background
Antigen Description
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and alergy.
Function
interleukin-4 receptor binding; protein binding
Gene ID
16189
Synonyms
IgG1; Il-4; BCGF, BCDF, B cell stimulating factor 1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra, Interleukin-4, IGG1 induction factor, B-cell IgG differentiation factor; Interleukin-4 Precursor; IL-4;BSF-1;B-cell growth factor 1
Download Datasheet:

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
Loading...
Contact Us

USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email: 

Europe
Tel: 44-207-048-3343


© 2007 - 2017 Creative-Biolabs All Rights Reserved