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Anti-ITGA5 Antibody (CAT#: MOM-18077)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human ITGA5 Antibody MOM-18077 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Chimeric (mouse/human) Antibody is directed against Human Integrin alpha 5 beta 1, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • Integrin alpha 5 beta 1
  • Type
  • Chimeric (mouse/human) IgG4
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in IF, IP, Neut, FuncS, ELISA, FC, IHC and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Protein Construction
  • Immunoglobulin G4, anti-(human a5b1 integrin) (human-mouse clone p200-M heavy chain), disulfide with human-mouse clone p200-M k-chain, dimer
  • Predicted N terminal
  • H Chain: MAVLGLL; L Chain: MDFQVQV
  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • This protein belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha V chain. Alpha chain V undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
  • Function
  • integrin binding; platelet-derived growth factor receptor binding; protein binding; receptor activity; vascular endothelial growth factor receptor 2 binding;
  • Synonyms
  • ITGA5; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); FNRA; integrin alpha-5; CD49e; VLA-5; integrin alpha-F; CD49 antigen-like family member E; fibronectin receptor subunit alpha; fibronectin receptor, alpha subunit; very late activation protein 5, alpha subunit; VLA5A;

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