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Anti-epor Antibody Fab (CAT#: MOM-18355-F(P))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human epor Antibody Fab Fragment MOM-18355-F(P) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is against Human EPOR, expressed in E. coli
  • Target
  • EPOR
  • Type
  • Fab
  • Immunogen
  • Human recombinant EPO Receptor (extracellular domain)
  • Species Reactivity
  • Human
  • Expression Host
  • E. coli
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >95.0%. Determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Storage
  • Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C.

BACKGROUND

  • Antigen Description
  • Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
  • Function
  • erythropoietin receptor activity; identical protein binding; protein binding; receptor activity;
  • Synonyms
  • EPOR; erythropoietin receptor; EPO-R; MGC138358

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