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Anti-icos Antibody Fab (CAT#: MOM-18383-F(E))

DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human icos Antibody Fab Fragment MOM-18383-F(E) 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Mouse Antibody Fab Fragment is directed against Human ICOS, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • ICOS
  • Type
  • Fab
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FC, IP, ELISA, Neut, FuncS, IF and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Purity
  • >95.0% as determined by analysis by SDS-PAGE.
  • Storage
  • At -20°C for one year.

BACKGROUND

  • Antigen Description
  • Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
  • Synonyms
  • ICOS; inducible T-cell co-stimulator; inducible T-cell costimulator; activation inducible lymphocyte immunomediatory molecule; AILIM; CD278; inducible costimulator; activation-inducible lymphocyte immunomediatory molecule; CVID1; MGC39850

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