The protein expression system is similar to a sophisticated instrument that continuously delivers proteins to the outside world. The central law is the simplest one which is that the terminal is theRead More…
Nuclear envelope (NE) consists of outer nuclear membrane (ONM) and inner nuclear membrane (INM), which are separated by the perinuclear space and connected at the nuclear pore complex. Inner nuclear membrane proteinsRead More…
Recently, a research paper entitled “Structural insights into the membrane microdomain organization by SPFH family proteins” was published in Cell Research. The high-resolution structure of super membrane complexes formed by two representativeRead More…
Lipid rafts are microstructural domains packed tightly in the plasma membrane and rich in cholesterol and sphingomyelin, which play an important role in many pathophysiological processes. Previously, researchers thought that the lipidRead More…
Deubiquitination Enzyme Regulates the Biosynthesis of Membrane Proteins Many proteins with hydrophobic transmembrane domain (TMD) can transfer from cytoplasm to cell membrane after translation. However, it is not clear how hydrophobic membraneRead More…
Structural Classification of Membrane Proteins Membrane proteins represent about a third of the proteins in living organisms. Based on their structure, there are main three types of membrane proteins: the first oneRead More…