anti-Bet v1 TCR, pMMP-IRES-GFP(TCR-L005)

The vector of anti-Bet v1 T cell receptor (TCR) is constructed for the engineering of T cell to target Birch Bet v1. The T cells are genetically modified through transduction with a retroviral vector expressing Bet v1-specific T cell receptor. And the vector product was designed for tolerance induction therapies in individuals with allergic and other immune-mediated diseases.


Details


Target
Bet v1
Target Species
Birch
Epitope
TNFKYNYSVIEGGPIG
Format
Non-modified TCR
HLA
HLA-DRB1
Targeting Diseases
Allergy
Vector Name
pMMP-IRES-GFP
Vector Length
3000bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
Bet v I allergen
Official Symbol
Bet v1
Synonyms
Bet v1; Bet v I; Bet v I allergen; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Allergy
Introduction
Bet v I allergen is a family of protein allergens. Allergies are hypersensitivity reactions of the immune system to specific substances called allergens (such as pollen, stings, drugs, or food) that, in most people, result in no symptoms.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Autoimmune Diseases

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CONTACT US

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45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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Tel: 44-207-048-3343

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