anti-NY-ESO-1 TCR, pLXSN(TCR-L085)

The vector of anti-NY-ESO-1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human NY-ESO-1. The T cells are genetically modified through transduction with a retroviral vector expressing NY-ESO-1-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.


Details


Target
NY-ESO-1
Target Species
Human
Epitope
PVPGVLLKEFTVSGNILTIRLTA
Format
Non-modified TCR
HLA
HLA-A*0201
Targeting Diseases
Melanoma
Vector Name
pLXSN
Vector Length
6714-6688bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
cancer/testis antigen 1A
Official Symbol
CTAG1A
Gene ID
UniProt ID
Synonyms
CTAG1A; CT6.1; CTAG; Cancer/Testis Antigen 6.1; Cancer/Testis Antigen 1; Autoimmunogenic Cancer/Testis Antigen NY-ESO-1; CTAG1; LAGE2A; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Melanoma
Introduction
The protein encoded by this gene is a tumor cell antigen found in various types of cancers, which makes it a good candidate for a cancer vaccine. This gene is also highly expressed in normal ovary and testis tissues. An identical copy of this gene is found on the same chromosome.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products


Carcinoma

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-048-3343

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