anti-pre-pro insulin (PPI) protein TCR, pSFG(TCR-L102)

The vector of anti-pre-pro insulin (PPI) protein T cell receptor (TCR) is constructed for the engineering of T cell to target Human pre-pro insulin (PPI) protein. The T cells are genetically modified through transduction with a retroviral vector expressing pre-pro insulin (PPI) protein-specific T cell receptor. And the vector product was designed for the treatment of diabetes .


Details


Target
pre-pro insulin (PPI) protein
Target Species
Human
Format
Cysteine-modified TCR
HLA
HLA-A2
Targeting Diseases
Diabetes
Vector Name
pSFG
Vector Length
8200bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
Preproinsulin
Official Symbol
PPI
Synonyms
PPI; pre-pro insulin protein; Preproinsulin; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; Diabetes
Introduction
Preproinsulin is the primary translational product of the INS gene. It is a peptide that is 110 amino acids in length. Preproinsulin is a proinsulin molecule with a signal peptide attached to its N-terminus.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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