anti-vesicular stomatitis virus octapeptide (VSV8) TCR, pMSGV1(TCR-L121)

The vector of anti-vesicular stomatitis virus octapeptide (VSV8) T cell receptor (TCR) is constructed for the engineering of T cell to target VSIV vesicular stomatitis virus octapeptide (VSV8). The T cells are genetically modified through transduction with a retroviral vector expressing vesicular stomatitis virus octapeptide (VSV8)-specific T cell receptor.


Details


Target
vesicular stomatitis virus octapeptide (VSV8)
Target Species
VSIV
Epitope
RGYVYQGL
Format
Non-modified TCR
Targeting Diseases
VSV Infection
Vector Name
pMSGV1
Vector Length
6700-8070bp
Vector Type
retroviral vector
Antibody Host
Human

Target


Gene Name
vesicular stomatitis virus octapeptide
Official Symbol
VSV8
Synonyms
gag; Gag; polyprotein; Human Immunodeficiency virus 1; Nucleocapsid protein p7; p15; p6 gag; Pr55Gag; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector; ADIS; HIV
Introduction
This octapeptide is amino acids 52 to 59 fragment of the the vesicular stomatitis virus (VSV) nucleoprotein. VSV-8 is derived from the VSV nucleoprotein that is expressed in the cytosol of the infected cells. CTL response against VSV in H-2Kb mice is directed against this single VSV-8 immunodominant peptide. This peptide forms complex with murine MHC class I molecule H-2Kb, which is similar to human HLA class I.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
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Tel: 44-207-048-3343

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