anti-vesicular stomatitis virus octapeptide (VSV8) TCR, pMSGV1(TCR-L121)
The vector of anti-vesicular stomatitis virus octapeptide (VSV8) T cell receptor (TCR) is constructed for the engineering of T cell to target VSIV vesicular stomatitis virus octapeptide (VSV8). The T cells are genetically modified through transduction with a retroviral vector expressing vesicular stomatitis virus octapeptide (VSV8)-specific T cell receptor.
vesicular stomatitis virus octapeptide (VSV8)
vesicular stomatitis virus octapeptide
VSIV8; VSIV-8; Vesicular Stomatitis Virus Nucleoprotein (52 - 59); Vesicular Stomatitis Virus Nucleoprotein; TCR; T cell receptor; transgenic TCR; antigen-specific T cell receptors; Engineering T-cell receptors; recombinant t cell receptors; specific t cell receptor; modified t cell receptor; retroviral vector
This octapeptide is amino acids 52 to 59 fragment of the the vesicular stomatitis virus (VSV) nucleoprotein. VSV-8 is derived from the VSV nucleoprotein that is expressed in the cytosol of the infected cells. CTL response against VSV in H-2Kb mice is directed against this single VSV-8 immunodominant peptide. This peptide forms complex with murine MHC class I molecule H-2Kb, which is similar to human HLA class I.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.