Besides the main categories of cancer such as Leukemia, Lymphoma, Carcinoma, Sarcoma, Blastoma and Germ cell tumors, Creative Biolabs also provides world class CAR products targeting other cancers like Glioma, tumor vasculature and even viral infection like CMV or EBV, etc,. Our many years of experience and the most advanced techniques enable us to offer you the first-class products according to your specific requirements.
Glioma is a kind of tumor which arises from glial cells in brain or spine. It can be divided into many types including Ependymomas, Astrocytomas, Oligodendrogliomas, Brainstem glioma, Optic nerve glioma and mixed gliomas. Benefiting from our broad experience in constructing CARs against various glioma antigens, we can offer you the best service.
Tumor regression mechanisms involve targeting both tumor antigen and tumor vasculature which helps tumor grow. Our skilled scientists and technicians have successfully constructed CARs targeting tumor vasculature antigens, including but not limited to KDR, VEGF-R2 and PSMA.
We are pleased to announce Creative Biolabs has successfully constructed different types of bispecific Chimeric Antigen Receptors (Calling Tan CAR) modified T cells approaches which make genetically engineered T cells recognize and target both cancer antigens and latent-virus antigens (such as from attack Cytomegalovirus (CMV), EBV or adenovirus).
In addition to the multiple cancer antigens, elite scientists from Creative Biolabs have successfully placed bispecific Chimeric Antigen Receptors (Calling Tan CAR) targeting cancer antigen grafted with latent-virus antigen in T cells to recognize and attack Cytomegalovirus (CMV) or EBV or adenovirus, which make genetically engineered T cells work better to react to the virus as well as to cancer cells.
From MIT news.
Products ordering information
Please note: We guarantee to offer you the best-in-class CARs products which can undoubtedly satisfy various customers' needs. If you are unable to find the item of your choice, please don't hesitate to contact us at any time.
|Associated malignancy or virus||Target antigen||Receptor type||Product|
|Glioma||Her2/neu||scFv-CD3ζ||pCDCAR1 ErbB2 h(ζ), T|
|Multiple malignancies||EGP-2||ScFv-CD28-CD3ζ (Influenza)||pCDCAR1 EGP-2 h(28ζ), T|
|EGP-2||ScFv-CD28-CD3ζ vs. CD3ζ||Inquiry|
|Various tumors||Mesothelin||ScFV-CD4-FcεRIγ||pCDCAR1 mesothelin h(γ), T|
|Mesothelin||ScFv-CD8-CD3ζ||pCDCAR1 mesothelin h(ζ), T|
|Mesothelin||ScFv-FceRIγ||pCDCAR1 mesothelin h(γ), T|
|Oncofetal antigen (h5T4)||scFv-FcεRIγ||Inquiry|
|TAA targeted by mAb IgE||ScFv-FcεRIγ||Inquiry|
|Tumor neovasculature||KDR||ScFV-CD3ζ (vaccination)||Inquiry|
|Prostate/tumor vasculature||PSMA||ScFv-FcεRIγ||pCDCAR1 PSMA h(FcεRIγ), T|
|PSMA||ScFv-FcεRIγ||pCDCAR1 PSMA h(FcεRIγ), T|
|Virus (CMV or EBV or adenovirus)||CD28||ScFv-FcεRIγ||Inquiry|
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