CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-871-5806
Europe: 44-207-048-3343
Fax: 1-631-207-8356
Email:

CAR Targeting Other Cancers and Viral Infection

Besides the main categories of cancer such as Leukemia, Lymphoma, Carcinoma, Sarcoma, Blastoma and Germ cell tumors, Creative Biolabs also provides world class CAR products targeting other cancers like Glioma, tumor vasculature and even viral infection like CMV or EBV, etc,. Our many years of experience and the most advanced techniques enable us to offer you the first-class products according to your specific requirements.

Glioma is a kind of tumor which arises from glial cells in brain or spine. It can be divided into many types including Ependymomas, Astrocytomas, Oligodendrogliomas, Brainstem glioma, Optic nerve glioma and mixed gliomas. Benefiting from our broad experience in constructing CARs against various glioma antigens, we can offer you the best service.

Tumor regression mechanisms involve targeting both tumor antigen and tumor vasculature which helps tumor grow. Our skilled scientists and technicians have successfully constructed CARs targeting tumor vasculature antigens, including but not limited to KDR, VEGF-R2 and PSMA.

We are pleased to announce Creative Biolabs has successfully constructed different types of bispecific Chimeric Antigen Receptors (Calling Tan CAR) modified T cells approaches which make genetically engineered T cells recognize and target both cancer antigens and latent-virus antigens (such as from attack Cytomegalovirus (CMV), EBV or adenovirus).

In addition to the multiple cancer antigens, elite scientists from Creative Biolabs have successfully placed bispecific Chimeric Antigen Receptors (Calling Tan CAR) targeting cancer antigen grafted with latent-virus antigen in T cells to recognize and attack Cytomegalovirus (CMV) or EBV or adenovirus, which make genetically engineered T cells work better to react to the virus as well as to cancer cells.

CAR Targeting Other Cancers and Viral Infection

From MIT news.

Products ordering information

Please note: We guarantee to offer you the best-in-class CARs products which can undoubtedly satisfy various customers' needs. If you are unable to find the item of your choice, please don't hesitate to contact us at any time.

Associated malignancy or virus Target antigen Receptor type Product
Glioma Her2/neu scFv-CD3ζ pCDCAR1 ErbB2 h(ζ), T
IL-13R-a2 ScFv-CD3ζ (EBV) Inquiry
Multiple malignancies EGP-2 ScFv-CD28-CD3ζ (Influenza) pCDCAR1 EGP-2 h(28ζ), T
EGP-2 ScFv-CD28-CD3ζ vs. CD3ζ Inquiry
Various tumors Mesothelin ScFV-CD4-FcεRIγ pCDCAR1 mesothelin h(γ), T
Mesothelin ScFv-CD8-CD3ζ pCDCAR1 mesothelin h(ζ), T
Mesothelin ScFv-FceRIγ pCDCAR1 mesothelin h(γ), T
NKG2D ligands ScFv-FcεRIγ Inquiry
Oncofetal antigen (h5T4) scFv-FcεRIγ Inquiry
TAA targeted by mAb IgE ScFv-FcεRIγ Inquiry
Tumor neovasculature KDR ScFV-CD3ζ (vaccination) Inquiry
VEGF-R2 ScFv-FcεRIγCAIX Inquiry
Prostate/tumor vasculature PSMA ScFv-FcεRIγ pCDCAR1 PSMA h(FcεRIγ), T
PSMA ScFv-FcεRIγ pCDCAR1 PSMA h(FcεRIγ), T
Virus (CMV or EBV or adenovirus) CD28 ScFv-FcεRIγ Inquiry

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-048-3343

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