As a leading technology service provider, Creative Biolabs provides customer with cutting-edge CellRapeutics™ Chimeric Antigen Receptors (CARs) against various antigens of sarcoma. Meanwhile, we can tailor our advanced technology services so as to meet your specific requirements, which can greatly accelerate the progress and improve the success rate of your project.
From Immuno-oncology news, © BioNews Services 2015.
Sarcoma is a cancer which usually occurs in connective tissues like bone or soft tissues. It can also develop in any other parts of the body. This kind of disease can be divided into two main types: Bone sarcomas and Soft tissue sarcomas. The traditional approaches for treating sarcoma include surgery, radiation therapy and chemotherapy, which always have severe side effects and less effectiveness. However, increasing evidences demonstrate that immunotherapy utilizing patients’ immune system can be developed as a novel powerful tool to attack cancer.
With many years of experience, experts from Creative Biolabs have constructed a series of CARs products targeting antigens from different types of sarcoma:
Bone sarcomas (osteosarcoma, Ewing’s sarcoma,and chondrosarcoma);
Soft tissue sarcomas (rhabdomyosarcoma and Leiomyosarcomas, Fibroblastic sarcomas, Liposarcomas, Synovial sarcomas, Vascular sarcomas, MPNST, GIST, etc)
Products against Sarcoma-specific antigens
Please note: New products updated every month. If you do not find the information meet your needs, please feel free to contact us. We are always here to assist you.
|Associated malignancy||Target antigen||Receptor type||Product|
|Advanced rcoma||Her2/neu||scFv-CD3ζ||pCDCAR1 ErbB2 h(ζ), T|
|Rhabdomyosarcoma||Fetal acethylcholine receptor||ScFv-CD3ζ||Inquiry|
|Other Sarcoma||MUC1||ScFv-4-1BB-CD3ζ||pCDCAR1 MUC1 h(BBζ), T|
|CSPG4||ScFv-CD28-4-1BB-CD3ζ||pCDCAR1 HMW-MAA h(28BBζ), T|
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