The vector of anti-PSMA chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human PSMA. The T cells are genetically modified through transduction with a retroviral vector expressing scFv of anti-PSMA antibody linked to CTLA-4 inhibitory signaling domains. And the vector product was designed for the treatment of prostate cancer.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-LC362||Anti-FOLH1×CD19 h(CD3ζ/CD28-41BB) Dual CAR, pCDCAR1|
|CAR-MZ035||Anti-PSMA scFv h(CTLA-4-CD3ζ) CAR, pCDCAR1|
|CAR-MZ034||Anti-PSMA scFv h(PD-1-CD3ζ) CAR, pCDCAR1|
|CAR-LC385||Anti-FOLH1 h(PD1) Inhibitory CAR, pCDCAR1|
|CAR-LC388||Anti-FOLH1 h(2B4) Inhibitory CAR, pCDCAR1|
|CAR-LC387||Anti-FOLH1 h(LAG3) Inhibitory CAR, pCDCAR1|
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