Anti-CAMEL T cell receptor (2/12), pCDTCR1(TCR-C023Z)

The vector of anti-CAMEL T cell receptor (TCR) is constructed for the engineering of T cell to target Human CAMEL. The T cells are genetically modified through transduction with a lentiviral vector expressing CAMEL-specific T cell receptor. And the vector product was designed for the treatment of Cancer.


Details


Target
CAMEL
Target Species
Human
Epitope
aa 46-65
Format
Non-modified
HLA
HLA-DR
Targeting Diseases
Melanoma, breast cancer, bladder cancer and prostate cancer
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
2/12
Antibody Host
Human

Target


Gene Name
Cancer/testis antigen 2
Official Symbol
CTAG2
Gene ID
UniProt ID
Synonyms
CTAG2; Cancer/testis antigen 2; CT2; ESO2; CAMEL; CT6.2; CT6.2a; CT6.2b; LAGE-1; LAGE2B
Introduction
This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Related Products


Carcinoma

Online Inquiry

Name:
Phone:
*E-mail Address:
*Service & Products Interested:
Project Description:
*Verification Code:
Please input "biolabs"(case insensitive) as verification code.
CB Promise
CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-871-5806
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

To view the contact information for a specific location, select the desired country:

Australia
australia

FOLLOW US ON