Anti-TYRP1 T cell receptor, pCDTCR1(TCR-C254Z)

The vector of anti-TYRP1 T cell receptor (TCR) is constructed for the engineering of T cell to target Human TYRP1. The T cells are genetically modified through transduction with a lentiviral vector expressing TYRP1-specific T cell receptor. And the vector product was designed for the treatment of Melanoma.


Details


Target
TYRP1
Target Species
Human
Epitope
aa 277-297
Format
Non-modified
HLA
HLA-DR4
Targeting Diseases
Melanoma
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Host
Human

Target


Gene Name
tyrosinase related protein 1
Official Symbol
TYRP1
Gene ID
UniProt ID
Synonyms
TYRP1; TRP; CAS2; CATB; GP75; OCA3; TRP1; TYRP; b-PROTEIN
Introduction
This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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