Anti-UL40 T cell receptor (KK50.4), pCDTCR1(TCR-C255Z)

The vector of anti-UL40 T cell receptor (TCR) is constructed for the engineering of T cell to target CMV UL40. The T cells are genetically modified through transduction with a lentiviral vector expressing UL40-specific T cell receptor. And the vector product was designed for the treatment of Cytomegalovirus infection.


Details


Target
UL40
Target Species
CMV
Epitope
VMAPRTLIL
Format
Non-modified
HLA
HLA-E*0103
Targeting Diseases
Cytomegalovirus infection
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
KK50.4
Antibody Host
Human

Target


Gene Name
Protein UL40
Official Symbol
UL40
UniProt ID
Synonyms
UL40; Protein UL40
Introduction
Plays a role in the protection against host NK-cell cytotoxicity by upregulating the cell surface expression of HLA-E independent of TAP (HLA-E has an inhibitory effect on the cytotoxic activity of the NK cell). Promotes also cell surface expression of UL18, another viral protein involved in NK-cell evasion.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Online Inquiry

Name:
Phone:
*E-mail Address:
*Service & Products Interested:
Project Description:
*Verification Code:
Please input "biolabs"(case insensitive) as verification code.
CB Promise
CONTACT US
45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-871-5806
Europe: 44-207-097-1828
Fax: 1-631-207-8356
Email:
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

Distributors

To view the contact information for a specific location, select the desired country:

Australia
australia

FOLLOW US ON