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CD19

Full Name:
CD19 molecule
Keywords:
CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T cell surface antigen Leu-12; B-lymphocyte surface antigen B4; Chronic Lymphocytic Leukemia; CLL; scFv; CD28; Leukemia; chimeric T cell receptors; chimeric immunoreceptors; chimeric antigen receptors; FMC63

Anti-CD19 scFv h(CD28) CARNK, pCDCAR1 (CAR-NK-1-M328-2)

Target Species: Human
Receptor Construction: scFv-CD28
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: First

Anti-CD19 scFv h(FcεRIγ) CARNK, pCDCAR1 (CAR-NK-1-M328-G)

Target Species: Human
Receptor Construction: scFv-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: First

Anti-CD19 scFv h(CD3ζ) CARNK, pCDCAR1 (CAR-NK-1-M328-Z)

Target Species: Human
Receptor Construction: scFv-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: First

Anti-CD19 scFv h(CD28-CD3ζ) CARNK, pCDCAR1 (CAR-NK-2-M328-2Z)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD4-FcεRIγ) CARNK, pCDCAR1 (CAR-NK-2-M328-4G)

Target Species: Human
Receptor Construction: scFv-CD4-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD4-CD3ζ) CARNK, pCDCAR1 (CAR-NK-2-M328-4Z)

Target Species: Human
Receptor Construction: scFv-CD4-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD8-CD3ζ) CARNK, pCDCAR1 (CAR-NK-2-M328-8Z)

Target Species: Human
Receptor Construction: scFv-CD8-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD28-FcεRIγ) CARNK, pCDCAR1 (CAR-NK-2-M328-BG)

Target Species: Human
Receptor Construction: scFv-CD28-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(41BB-CD3ζ) CARNK, pCDCAR1 (CAR-NK-2-M328-BZ)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(b2c-CD3ζ) CARNK, pCDCAR1 (CAR-NK-2-M328-CZ)

Target Species: Human
Receptor Construction: scFv-b2c-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD28-41BB-CD3ζ) CARNK, pCDCAR1 (CAR-NK-3-M328-2BZ)

Target Species: Human
Receptor Construction: scFv-CD28-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 scFv h(CD28-OX40-CD3ζ) CARNK, pCDCAR1 (CAR-NK-3-M328-2XZ)

Target Species: Human
Receptor Construction: scFv-CD28-OX40-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 scFv h(CD28) CART, pCDCAR1 (CAR-T-1-L332-2)

Target Species: Human
Receptor Construction: scFv-CD28
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: First

Anti-CD19 scFv h(FcεRIγ) CART, pCDCAR1 (CAR-T-1-L332-G)

Target Species: Human
Receptor Construction: scFv-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: First

Anti-CD19 scFv h(CD3ζ) CART, pCDCAR1 (CAR-T-1-L332-Z)

Target Species: Human
Receptor Construction: scFv-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: First

Anti-CD19 scFv h(CD28-FcεRIγ) CART, pCDCAR1 (CAR-T-2-L332-2G)

Target Species: Human
Receptor Construction: scFv-CD28-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD28-CD3ζ) CART, pCDCAR1 (CAR-T-2-L332-2Z)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD4-FcεRIγ) CART, pCDCAR1 (CAR-T-2-L332-4G)

Target Species: Human
Receptor Construction: scFv-CD4-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD4-CD3ζ) CART, pCDCAR1 (CAR-T-2-L332-4Z)

Target Species: Human
Receptor Construction: scFv-CD4-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD8-CD3ζ) CART, pCDCAR1 (CAR-T-2-L332-8Z)

Target Species: Human
Receptor Construction: scFv-CD8-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(41BB-CD3ζ) CART, pCDCAR1 (CAR-T-2-L332-BZ)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(b2c-CD3ζ) CART, pCDCAR1 (CAR-T-2-L332-CZ)

Target Species: Human
Receptor Construction: scFv-b2c-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 (CAR-T-3-L332-2BZ)

Target Species: Human
Receptor Construction: scFv-CD28-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 (CAR-T-3-L332-2XZ)

Target Species: Human
Receptor Construction: scFv-CD28-OX40-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia (CLL)
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (Denintuzumab) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC004)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Denintuzumab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (47G4) h(CD28-CD3ζ) CAR, pCDCAR1 (CAR-LC009)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 47G4
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (47G4) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC010)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 47G4
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (47G4) h(CD27-CD3ζ) CAR, pCDCAR1 (CAR-LC011)

Target Species: Human
Receptor Construction: scFv-CD27-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 47G4
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (47G4) h(CD28-CD27-CD3ζ) CAR, pCDCAR1 (CAR-LC012)

Target Species: Human
Receptor Construction: scFv-CD28-CD27-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 47G4
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (47G4) h(41BB-CD27-CD3ζ) CAR, pCDCAR1 (CAR-LC013)

Target Species: Human
Receptor Construction: scFv-41BB-CD27-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 47G4
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (47G4) h(CD28-CD27-FcεRIγ) CAR, pCDCAR1 (CAR-LC014)

Target Species: Human
Receptor Construction: scFv-CD28-CD27-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 47G4
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (47G4) h(CD28-FcεRIγ) CAR, pCDCAR1 (CAR-LC015)

Target Species: Human
Receptor Construction: scFv-CD28-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 47G4
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (FMC63) h(CD28-CD27-FcεRIγ) CAR, pCDCAR1 (CAR-LC016)

Target Species: Human
Receptor Construction: scFv-CD28-CD27-FcεRIγ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (104875) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC142)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 104875
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (104876) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC143)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 104876
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (104877) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC144)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 104877
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (104878) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC145)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 104878
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (104879) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC146)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 104879
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (104880) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC147)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 104880
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (104881) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC148)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 104881
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (104882) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC149)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 104882
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (105974) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC150)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 105974
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (105975) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC151)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 105975
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (105976) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC152)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 105976
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (105977) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC153)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 105977
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (CTL019) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC154)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: CTL019
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (h119a) h(CD28-CD3ζ) CAR, pCDCAR1 (CAR-LC163)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: h119a
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (Coltuximab) h(CD3ζ) CAR, pCDCAR1 (CAR-LC184)

Target Species: Human
Receptor Construction: scFv-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Coltuximab
Vector Name: pCDCAR1
Generation: First

Anti-CD19 (Denintuzumab) h(CD28-CD3ζ) CAR, pCDCAR1 (CAR-LC185)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Denintuzumab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (Coltuximab) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC186)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Coltuximab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (SJ25C1) h(CD28-CD3ζ) CAR, pCDCAR1 (CAR-LC193)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: SJ25C1
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 h(CD2-CD3ζ) CAR, pCDCAR1 (CAR-LC225)

Target Species: Human
Receptor Construction: scFv-CD2-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (S1) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC229)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: S1
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (S1) h(CD28-CD3ζ) CAR, pCDCAR1 (CAR-LC230)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: S1
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (S1) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC231)

Target Species: Human
Receptor Construction: scFv-CD28-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: S1
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (S2) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC232)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: S2
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (S2) h(CD28-CD3ζ) CAR, pCDCAR1 (CAR-LC233)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: S2
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (S2) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC234)

Target Species: Human
Receptor Construction: scFv-CD28-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: S2
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 h(VNAR-41BB-CD3ζ) CAR, pCDCAR1 (CAR-LC254)

Target Species: Human
Receptor Construction: VNAR-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 h(CD3ζ, RXR/EcR) Conditional CAR, pCDCAR1 (CAR-LC273)

Target Species: Human
Receptor Construction: scFv-RXR/EcR-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Denintuzumab
Vector Name: pCDCAR1
Generation: First

Anti-CD19 h(CD28-OX40-CD3ζ, FKBP12/FRB) Conditional CAR, pCDCAR1 (CAR-LC274)

Target Species: Human
Receptor Construction: scFv-FKBP12/FRB-CD28-OX40-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Denintuzumab
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 h(41BB-CD3ζ, FKBP/FRB) Conditional CAR, pCDCAR1 (CAR-LC277)

Target Species: Human
Receptor Construction: scFv-FKBP12 (DmrA)/FRB (DmrC)-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Denintuzumab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (FMC63) h(41BB-CD3ζ, K4/E4) Conditional CAR, pCDCAR1 (CAR-LC278)

Target Species: Human
Receptor Construction: Fab-K4/E4-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (FMC63) h(41BB-CD3ζ, K4/E4) Conditional CAR, pCDCAR1 (CAR-LC279)

Target Species: Human
Receptor Construction: Fab-E4/K4-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (4G7) h(41BB-CD3ζ) Multi-chain CAR, pCDCAR1 (CAR-LC294)

Target Species: Human
Receptor Construction: FcRα-scFv-CD8/FcRβ/FcRγ-ΔITAM-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 4G7
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (4G7) h(CD3ζ) Multi-chain CAR, pCDCAR1 (CAR-LC295)

Target Species: Human
Receptor Construction: FcRα-scFv-CD8/FcRβ-ΔITAM-41BB/FcRγ-ΔITAM-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 4G7
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (4G7) h(41BB-CD3ζ) Multi-chain CAR, pCDCAR1 (CAR-LC296)

Target Species: Human
Receptor Construction: FcRα-scFv-CD8/FcRβ-ΔITAM-41BB-CD3ζ/FcRγ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 4G7
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (4G7) h(41BB/CD3ζ) Multi-chain CAR, pCDCAR1 (CAR-LC297)

Target Species: Human
Receptor Construction: FcRα-scFv-CD8/FcRβ-41BB/FcRγ-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 4G7
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (4G7) h(41BB) Multi-chain CAR, pCDCAR1 (CAR-LC298)

Target Species: Human
Receptor Construction: FcRα-scFv-CD8-41BB/FcRβ/FcRγ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 4G7
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (4G7) h(41BB/CD3ζ) Multi-chain CAR, pCDCAR1 (CAR-LC299)

Target Species: Human
Receptor Construction: FcRα-scFv-CD8-41BB/FcRβ-ΔITAM-CD3ζ/FcRγ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 4G7
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (4G7) h(41BB/CD3ζ) Multi-chain CAR, pCDCAR1 (CAR-LC300)

Target Species: Human
Receptor Construction: FcRα-scFv-CD8-41BB/FcRβ/FcRγ-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 4G7
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (4G7) h(CD28/41BB/CD3ζ) Multi-chain CAR, pCDCAR1 (CAR-LC301)

Target Species: Human
Receptor Construction: FcRα-scFv-CD8-CD28/FcRβ-ΔITAM-41BB/FcRγ-ΔITAM-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: 4G7
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (FMC63) h(41BB-CD3ζ, Strep Tag) Marked CAR, pCDCAR1 (CAR-LC348)

Target Species: Human
Receptor Construction: scFv-Strep Tag-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (Blinatumomab) h(CD28-CD3ζ, EGFRt) Marked CAR, pCDCAR1 (CAR-LC350)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ-EGFRt
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Blinatumomab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (Denintuzumab) h(41BB-CD3ζ, Her2t) Marked CAR, pCDCAR1 (CAR-LC353)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ/Her2t
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Denintuzumab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (Inebilizumab) h(CD28-CD3ζ, Anti-CD47 ()) Armoured CAR, pCDCAR1 (CAR-LC369)

Target Species: Human
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Inebilizumab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (Denintuzumab) h(CD28-CD3ζ,iCasp-9, IL-15) Self-destruct CAR, pCDCAR1 (CAR-LC381)

Target Species: Human
Receptor Construction: iCasp9-2A-scFv-CD28-CD3ζ-2A-IL-15
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Denintuzumab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (FMC63) h(41BB-CD3ζ,CD20) Self-destruct CAR, pCDCAR1 (CAR-LC382)

Target Species: Human
Receptor Construction: CD20-scFv-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: FMC63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (Blinatumomab) h(CD28-CD3ζ,CD20) Self-destruct CAR, pCDCAR1 (CAR-LC383)

Target Species: Human
Receptor Construction: scFv-CD20-41BB-CD3ζ
Targeting Diseases: Chronic lymphocytic leukemia
Antibody Clone: Blinatumomab
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (SJ25C1) h(CD3ζ) CAR, pCDCAR1 (CAR-MZ125)

Target Species: Human
Receptor Construction: scFv-CD3ζ
Targeting Diseases: Acute lymphoblastic leukemia
Antibody Clone: SJ25C1
Vector Name: pCDCAR1
Generation: First

Anti-CD19 (SJ25C1) h(DAP10-CD3ζ) CAR, pCDCAR1 (CAR-MZ127)

Target Species: Human
Receptor Construction: scFv-DAP10-CD3ζ
Targeting Diseases: Acute lymphoblastic leukemia
Antibody Clone: SJ25C1
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (SJ25C1) h(CD3ζ-DAP10) CAR, pCDCAR1 (CAR-MZ128)

Target Species: Human
Receptor Construction: scFv-CD3ζ-DAP10
Targeting Diseases: Acute lymphoblastic leukemia
Antibody Clone: SJ25C1
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (SJ25C1) h(41BB-CD3ζ) CAR, pCDCAR1 (CAR-MZ129)

Target Species: Human
Receptor Construction: scFv-41BB-CD3ζ
Targeting Diseases: Acute lymphoblastic leukemia
Antibody Clone: SJ25C1
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (SJ25C1) h(OX-40-CD3ζ) CAR, pCDCAR1 (CAR-MZ130)

Target Species: Human
Receptor Construction: scFv-OX40-CD3ζ
Targeting Diseases: Acute lymphoblastic leukemia
Antibody Clone: SJ25C1
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 scFv h(CD3ζ-41BB) CAR, pCDCAR1 (CAR-MZ131)

Target Species: Human
Receptor Construction: scFv-CD3ζ-41BB
Targeting Diseases: Children with Relapsed/Refractory Acute lymphoblastic leukemia
Vector Name: pCDCAR1
Generation: Second

Lenti-CD19 CAR (scFv-CD28, FMC63) Viral Particle (VP-CAR-LC61)

Target: CD19
Receptor Construction: scFv (FMC63)-CD28
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-FcεRIγ, FMC63) Viral Particle (VP-CAR-LC62)

Target: CD19
Receptor Construction: scFv (FMC63)-FcεRIγ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD3ζ, FMC63) Viral Particle (VP-CAR-LC63)

Target: CD19
Receptor Construction: scFv (FMC63)-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-FcεRIγ, FMC63) Viral Particle (VP-CAR-LC64)

Target: CD19
Receptor Construction: scFv (FMC63)-CD28-FcεRIγ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD3ζ, FMC63) Viral Particle (VP-CAR-LC65)

Target: CD19
Receptor Construction: scFv (FMC63)-CD28-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD4-FcεRIγ, FMC63) Viral Particle (VP-CAR-LC66)

Target: CD19
Receptor Construction: scFv (FMC63)-CD4-FcεRIγ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD4-CD3ζ, FMC63) Viral Particle (VP-CAR-LC67)

Target: CD19
Receptor Construction: scFv (FMC63)-CD4-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD8-CD3ζ, FMC63) Viral Particle (VP-CAR-LC68)

Target: CD19
Receptor Construction: scFv (FMC63)-CD8-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, FMC63) Viral Particle (VP-CAR-LC69)

Target: CD19
Receptor Construction: scFv (FMC63)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-b2c-CD3ζ, FMC63) Viral Particle (VP-CAR-LC70)

Target: CD19
Receptor Construction: scFv (FMC63)-b2c-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-41BB-CD3ζ, FMC63) Viral Particle (VP-CAR-LC71)

Target: CD19
Receptor Construction: scFv (FMC63)-CD28-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-OX40-CD3ζ, FMC63) Viral Particle (VP-CAR-LC72)

Target: CD19
Receptor Construction: scFv (FMC63)-CD28-OX40-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD3ζ, 47G4) Viral Particle (VP-CAR-LC515)

Target: CD19
Receptor Construction: scFv (47G4)-CD28-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 47G4) Viral Particle (VP-CAR-LC516)

Target: CD19
Receptor Construction: scFv (47G4)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD27-CD3ζ, 47G4) Viral Particle (VP-CAR-LC517)

Target: CD19
Receptor Construction: scFv (47G4)-CD27-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD27-CD3ζ, 47G4) Viral Particle (VP-CAR-LC518)

Target: CD19
Receptor Construction: scFv (47G4)-CD28-CD27-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD27-CD3ζ, 47G4) Viral Particle (VP-CAR-LC519)

Target: CD19
Receptor Construction: scFv (47G4)-41BB-CD27-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD27-FcεRIγ, 47G4) Viral Particle (VP-CAR-LC520)

Target: CD19
Receptor Construction: scFv (47G4)-CD28-CD27-FcεRIγ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-FcεRIγ, 47G4) Viral Particle (VP-CAR-LC521)

Target: CD19
Receptor Construction: scFv (47G4)-CD28-FcεRIγ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD27-FcεRIγ, FMC63) Viral Particle (VP-CAR-LC522)

Target: CD19
Receptor Construction: scFv (FMC63)-CD28-CD27-FcεRIγ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 104875) Viral Particle (VP-CAR-LC626)

Target: CD19
Receptor Construction: scFv (104875)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 104876) Viral Particle (VP-CAR-LC627)

Target: CD19
Receptor Construction: scFv (104876)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 104877) Viral Particle (VP-CAR-LC628)

Target: CD19
Receptor Construction: scFv (104877)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 104878) Viral Particle (VP-CAR-LC629)

Target: CD19
Receptor Construction: scFv (104878)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 104879) Viral Particle (VP-CAR-LC630)

Target: CD19
Receptor Construction: scFv (104879)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 104880) Viral Particle (VP-CAR-LC631)

Target: CD19
Receptor Construction: scFv (104880)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 104881) Viral Particle (VP-CAR-LC632)

Target: CD19
Receptor Construction: scFv (104881)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 104882) Viral Particle (VP-CAR-LC633)

Target: CD19
Receptor Construction: scFv (104882)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 105974) Viral Particle (VP-CAR-LC634)

Target: CD19
Receptor Construction: scFv (105974)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 105975) Viral Particle (VP-CAR-LC635)

Target: CD19
Receptor Construction: scFv (105975)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 105976) Viral Particle (VP-CAR-LC636)

Target: CD19
Receptor Construction: scFv (105976)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, 105977) Viral Particle (VP-CAR-LC637)

Target: CD19
Receptor Construction: scFv (105977)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, CTL019) Viral Particle (VP-CAR-LC638)

Target: CD19
Receptor Construction: scFv (CTL019)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD3ζ, h119a) Viral Particle (VP-CAR-LC647)

Target: CD19
Receptor Construction: scFv (h119a)-CD28-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD3ζ, SJ25C1) Viral Particle (VP-CAR-LC671)

Target: CD19
Receptor Construction: scFv (SJ25C1)-CD28-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, S1) Viral Particle (VP-CAR-LC701)

Target: CD19
Receptor Construction: scFv (S1)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD3ζ, S1) Viral Particle (VP-CAR-LC702)

Target: CD19
Receptor Construction: scFv (S1)-CD28-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-41BB-CD3ζ, S1) Viral Particle (VP-CAR-LC703)

Target: CD19
Receptor Construction: scFv (S1)-CD28-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, S2) Viral Particle (VP-CAR-LC704)

Target: CD19
Receptor Construction: scFv (S2)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-CD3ζ, S2) Viral Particle (VP-CAR-LC705)

Target: CD19
Receptor Construction: scFv (S2)-CD28-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD28-41BB-CD3ζ, S2) Viral Particle (VP-CAR-LC706)

Target: CD19
Receptor Construction: scFv (S2)-CD28-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD3ζ, SJ25C1) Viral Particle (VP-CAR-LC824)

Target: CD19
Receptor Construction: scFv (SJ25C1)-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-DAP10-CD3ζ, SJ25C1) Viral Particle (VP-CAR-LC825)

Target: CD19
Receptor Construction: scFv (SJ25C1)-DAP10-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-CD3ζ-DAP10, SJ25C1) Viral Particle (VP-CAR-LC826)

Target: CD19
Receptor Construction: scFv (SJ25C1)-CD3ζ-DAP10
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-41BB-CD3ζ, SJ25C1) Viral Particle (VP-CAR-LC827)

Target: CD19
Receptor Construction: scFv (SJ25C1)-41BB-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Lenti-CD19 CAR (scFv-OX40-CD3ζ, SJ25C1) Viral Particle (VP-CAR-LC828)

Target: CD19
Receptor Construction: scFv (SJ25C1)-OX40-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus

Anti-CD19 scFv h(CTLA4-CD3ζ) CAR, pCDCAR1 (CAR-MZ001)

Target Species: Human
Receptor Construction: scFv-CTLA4-CD3ζ
Targeting Diseases: CD19 positive cancers
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (1D3) h(CD28-CD3ζ) CAR, pCDCAR1 (CAR-MZ020)

Target Species: Murine
Receptor Construction: scFv-CD28-CD3ζ
Targeting Diseases: Advanced B-cell malignancies
Antibody Clone: 1D3
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (Denintuzumab) scFv h(CD3ζ) CAR, pCDCAR1 (CAR-MZ048)

Target Species: Human
Receptor Construction: scFv-CD3ζ
Targeting Diseases: Primary human pre-B-cell acute lymphoblastic leukemia
Antibody Clone: Denintuzumab
Vector Name: pCDCAR1
Generation: First

Anti-CD19 scFv h(41BB-CD28-CD3ζ) CAR, pCDCAR1 (CAR-MZ052)

Target Species: Human
Receptor Construction: scFv-CD28-41BB-CD3ζ
Targeting Diseases: Primary human pre-B-cell acute lymphoblastic leukemia
Vector Name: pCDCAR1
Generation: Third

Anti-CD19 (FMC-63) h(2B4) CAR, pCDCAR1 (CAR-MZ095)

Target Species: Human
Receptor Construction: scFv-2B4
Targeting Diseases: Leukemia and Neuroblastoma
Antibody Clone: FMC-63
Vector Name: pCDCAR1
Generation: First

Anti-CD19 (FMC-63) h(2B4-CD3ζ) CAR, pCDCAR1 (CAR-MZ096)

Target Species: Human
Receptor Construction: scFv-2B4-CD3ζ
Targeting Diseases: Leukemia and Neuroblastoma
Antibody Clone: FMC-63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19 (FMC-63) h(t2B4) CAR, pCDCAR1 (CAR-MZ097)

Target Species: Human
Receptor Construction: scFv-t2B4
Targeting Diseases: Leukemia and Neuroblastoma
Antibody Clone: FMC-63
Vector Name: pCDCAR1
Generation: First

Anti-CD19 (FMC-63) h(t2B4-CD3ζ) CAR, pCDCAR1 (CAR-MZ098)

Target Species: Human
Receptor Construction: scFv-t2B4-CD3ζ
Targeting Diseases: Leukemia and Neuroblastoma
Antibody Clone: FMC-63
Vector Name: pCDCAR1
Generation: Second

Anti-CD19×HER2 scFv h(CD3ζ) TanCAR, pCDCAR1 (CAR-MZ244)

Target Species: Human
Receptor Construction: CD19 scFv-HER2 scFv-CD3ζ
Targeting Diseases: CD19+/HER2+ cancers
Vector Name: pCDCAR1
Generation: First

Anti-CD19×HER2 scFv h(41BB-CD3ζ) TanCAR, pCDCAR1 (CAR-MZ246)

Target Species: Human
Receptor Construction: CD19 scFv-HER2 scFv-41BB-CD3ζ
Targeting Diseases: CD19+/HER2+ cancers
Vector Name: pCDCAR1
Generation: Second

Anti-CD19×HER2 scFv h(CD28-41BB-CD3ζ) TanCAR, pCDCAR1 (CAR-MZ247)

Target Species: Human
Receptor Construction: CD19 scFv-HER2 scFv-CD28-41BB-CD3ζ
Targeting Diseases: CD19+/HER2+ cancers
Vector Name: pCDCAR1
Generation: Third

Lenti-CD19 CAR (scFv-CD28-CD3ζ, 1D3) Viral Particle (VP-CAR-LC749)

Target: CD19
Receptor Construction: scFv (1D3)-CD28-CD3ζ
Gene Insert: Chimeric Antigen Receptor
Packaging System: Lentivirus
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