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B Cell Maturation Antigen (BCMA), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17),is encoded by TNFRSF17 gene in human. It is a transmembrane signaling protein preferentially expressed on plasma cells. It is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF). Its ligands including BAFF and A Proliferation Inducing Ligand (APRIL). BCMA is involved in JNK and NF-kB activation pathways that induce B-cell development and autoimmune responses. BCMA has been implicated in autoimmune disorders as well as B-lymphocyte malignancies, leukemia, lymphomas, and multiple myeloma.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| XS-0323-ZP7 | Anti-BCMA (25D2 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | 25D2 | Humanized | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP8 | Anti-BCMA (FCARH143 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | FCARH143 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP9 | Anti-BCMA (P-BCMA-101 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | P-BCMA-101 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP10 | Anti-BCMA (CT053 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | CT053 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP11 | Anti-BCMA (A7D12.2 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | A7D12.2 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP12 | Anti-BCMA (11D5-3 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | 11D5-3 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP13 | Anti-BCMA (BCMA/2366 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | BCMA/2366 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP14 | Anti-BCMA (E6D7B scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | E6D7B | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP650 | Anti-BCMA (BCMA(171) scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | BCMA(171) | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP651 | Anti-BCMA (BCMA(125) scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | BCMA(125) | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP652 | Anti-BCMA (FHVH33 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | FHVH33 | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP653 | Anti-BCMA (JCARH125 scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | JCARH125 | Human | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP662 | Anti-BCMA (J22.9-xi scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | J22.9-xi | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP699 | Anti-BCMA (1E1E scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | 1E1E | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-ZP700 | Anti-BCMA (2D4A scFv-CD28TM-CD79β) CBCR(CAR-B), pCDCAR1 | Human | 2D4A | Mouse | scFv-CD28TM-CD79β | Lentiviral vector | T cell | CAR-B Vector | |
| XS-0323-LX179 | Anti-BCMA VHH(X3XH179) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH179 | VHH-CD28-41BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX180 | Anti-BCMA VHH(X3XH180) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH180 | VHH-CD28-41BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX181 | Anti-BCMA VHH(X3XH181) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH181 | VHH-CD28-41BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX182 | Anti-BCMA VHH(X3XH182) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH182 | VHH-CD28-41BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0323-LX183 | Anti-BCMA VHH(X3XH183) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector | Human | X3XH183 | VHH-CD28-41BB-CD3ζ | Lentiviral vector | T cell | CAR-T | ||
| XS-0823-LX2 | Anti-hBCMA (AB) ICD(CD28-OX40-CD3ζ) CAR-MA, pAd5f35 Vector | Human | AB | Adenoviral vectors |
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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