All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.
CAT | Product Name | Target Species | TCR Clone | Host Species | Epitope | Allele | Vector Type | Inquiry & Datasheet |
TCR-C021Z | Human anti-CAMEL T cell receptor (2/52), pCDTCR1 | Human | 2/52 | Human | aa 19-27 (AAQERRVPR) | HLA-DR | Lentiviral | |
TCR-C022Z | Human anti-CAMEL T cell receptor (2/54), pCDTCR1 | Human | 2/54 | Human | aa 19-27 (AAQERRVPR) | HLA-DR | Lentiviral | |
TCR-C023Z | Human anti-CAMEL T cell receptor (2/12), pCDTCR1 | Human | 2/12 | Human | aa 46-65 | HLA-DR | Lentiviral | |
TCR-C024Z | Human anti-CAMEL T cell receptor (2/33), pCDTCR1 | Human | 2/33 | Human | aa 1-20 | HLA-DR | Lentiviral |
The latest newsletter to introduce the latest breaking information, our site updates, field and other scientific news, important events, and insights from industry leaders
LEARN MORE NEWSLETTERCellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
LEARN MORE SOLUTIONSilence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
LEARN MORE NOVEL TECHNOLOGYCanine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
LEARN MORE SOLUTION