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CD23 (Cluster of Differentiation 23), also known as FcεRII, is a "low-affinity" receptor for immunoglobulin E (IgE). It plays an important roll in regulation of IgE levels. CD23 is a C-type lectin, usually found on mature B cells, activatd macrophages,eosiophis, follicular denditic cells and platelets. CD23 is one of the most useful markers for identifying B cell chronic lymphocytic leukemia(CLL). Lymphomas arising from the mantle zone are generally negative for CD23, but most B-cell chronic lymphomocytic leukaemias and low-grade B-cell lymphomas are positive.
CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
CAR-T-1-M309-2 | Anti-CD23 scFv h(CD28) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD28 | Lentiviral | T cell | ||
CAR-T-1-M309-G | Anti-CD23 scFv h(FcεRIγ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-FcεRIγ | Lentiviral | T cell | ||
CAR-T-1-M309-Z | Anti-CD23 scFv h(CD3ζ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD3ζ | Lentiviral | T cell | ||
CAR-T-2-M309-2G | Anti-CD23 scFv h(CD28-FcεRIγ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD28-FcεRIγ | Lentiviral | T cell | ||
CAR-T-2-M309-2Z | Anti-CD23 scFv h(CD28-CD3ζ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD28-CD3ζ | Lentiviral | T cell | ||
CAR-T-2-M309-4G | Anti-CD23 scFv h(CD4-FcεRIγ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD4-FcεRIγ | Lentiviral | T cell | ||
CAR-T-2-M309-4Z | Anti-CD23 scFv h(CD4-CD3ζ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD4-CD3ζ | Lentiviral | T cell | ||
CAR-T-2-M309-8Z | Anti-CD23 scFv h(CD8-CD3ζ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD8-CD3ζ | Lentiviral | T cell | ||
CAR-T-2-M309-BZ | Anti-CD23 scFv h(41BB-CD3ζ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-41BB-CD3ζ | Lentiviral | T cell | ||
CAR-T-2-M309-CZ | Anti-CD23 scFv h(b2c-CD3ζ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-b2c-CD3ζ | Lentiviral | T cell | ||
CAR-T-3-M309-2BZ | Anti-CD23 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD28-41BB-CD3ζ | Lentiviral | T cell | ||
CAR-T-3-M309-2XZ | Anti-CD23 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1 | Human | Tü1 | Mouse | scFv-CD28-OX40-CD3ζ | Lentiviral | T cell | ||
CAR-MZ206 | Anti-CD23 (C11) h(CD3ζ) CAR, pCDCAR1 | Human | C11 | Mouse | scFv-CD3ζ | Retroviral | T cell | ||
CAR-MZ207 | Anti-CD23 (C11) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | C11 | Mouse | scFv-CD28-CD3ζ | Retroviral | T cell | ||
CAR-MZ208 | Anti-CD23 (C11) h(CD28-41BB-CD3ζ) CAR, pCDCAR1 | Human | C11 | Mouse | scFv-CD28-41BB-CD3ζ | Retroviral | T cell | ||
CAR-MZ209 | Anti-CD23 (C11) h(CD28-OX40-CD3ζ) CAR, pCDCAR1 | Human | C11 | Mouse | scFv-CD28-OX40-CD3ζ | Retroviral | T cell | ||
XS-0922-ZP805 | Anti-CD23 (5E8) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 5E8 | Primate | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
XS-0922-ZP806 | Anti-CD23 (5E8) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | 5E8 | Primate | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
XS-0922-ZP807 | Anti-CD23 (lumiliximab) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | lumiliximab | Chimeric | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
XS-0922-ZP808 | Anti-CD23 (lumiliximab) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | lumiliximab | Chimeric | scFv-41BB-CD3ζ | Lentiviral vector | T cell |
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