CEA

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e (Cluster of Differentiation 66e), is a protein encoded by CEACAM5 gene in human. Carcinoembryonic antigen (CEA) describes a set of highly related glycoproteins involved in cell adhesion. CEA is normally produced in gastrointestinal tissue during fetal development, but the production stops before birth. Therefore, CEA is usually present only at very low levels in the blood of healthy adults. However, the serum levels are raised in some types of cancer, so that CEA usually act as a tumor marker in clinical test. CEA are glycosyl phosphatidyl inositol (GPI) cell-surface-anchored glycoproteins whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.

Associated Disease
Anti-CEA CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC019 T cell Second Arcitumomab ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-LC020 T cell Second Labetuzumab ~8kb Retroviral scFv-CD3ζ-CD28 Human Inquiry
CAR-LC368 T cell First Arcitumomab ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-LC375 T cell Second Labetuzumab ~8kb Retroviral scFv-CD28-CD3ζ-GITR Human Inquiry
CAR-MZ042 T cell Second BW431/26 ~8kb Retroviral scFv-CD3ζ-OX40 Human Inquiry
CAR-MZ087 T cell First SCA431 ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ088 T cell Second SCA431 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ089 T cell Second SCA431 ~8kb Retroviral scFv-OX40-CD3ζ Mouse Inquiry
CAR-MZ090 T cell Third SCA431 ~8kb Retroviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CAR-MZ105 T cell First MFE23 ~8kb Retroviral scFv-CD3ζ Mouse Inquiry
CAR-MZ106 T cell Second MFE23 ~8kb Retroviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ107 T cell Second MFE23 ~8kb Retroviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ108 T cell Third MFE23 ~8kb Retroviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-MZ144 T cell Second F11-39 ~8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-MZ145 T cell Second F11-39 ~8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-MZ146 T cell Third F11-39 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-MZ170 T cell First C2-45 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-MZ171 T cell Second C2-45 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ172 T cell Third C2-45 ~8kb Lentiviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-T-1-M314-2 T cell First BW431/26 8kb Lentiviral scFv-CD28 Human Inquiry
CAR-T-1-M314-G T cell First BW431/26 8kb Lentiviral scFv-FcεRIγ Human Inquiry
CAR-T-1-M314-Z T cell First BW431/26 8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-T-2-M314-2G T cell Second BW431/26 8kb Lentiviral scFv-CD28-FcεRIγ Human Inquiry
CAR-T-2-M314-2Z T cell Second BW431/26 8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-T-2-M314-4G T cell Second BW431/26 8kb Lentiviral scFv-CD4-FcεRIγ Human Inquiry
CAR-T-2-M314-4Z T cell Second BW431/26 8kb Lentiviral scFv-CD4-CD3ζ Human Inquiry
CAR-T-2-M314-8Z T cell Second BW431/26 8kb Lentiviral scFv-CD8-CD3ζ Human Inquiry
CAR-T-2-M314-BZ T cell Second BW431/26 8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
CAR-T-2-M314-CZ T cell Second BW431/26 8kb Lentiviral scFv-b2c-CD3ζ Human Inquiry
CAR-T-3-M314-2BZ T cell Third BW431/26 8kb Lentiviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-T-3-M314-2XZ T cell Third BW431/26 8kb Lentiviral scFv-CD28-OX40-CD3ζ Human Inquiry
Anti-CEA TCR Product list:
Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Type Epitope Format HLA Data
sheet
Price
TCR-C035Z Human Mouse ~8kb Lentiviral IMIGVLVGV Affinity enhanced HLA-A*0201 Inquiry
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