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EXPLORE MORECreative Biolabs has a tradition of commitment. To achieve efficient execution and regulatory approval, we offer careful considerations of your program for the development of a cellular or gene therapy product – now and in the future.
EXPLORE MORE HighlightsWe focus on unmet needs and develop novel cellular and gene drugs and solutions that offer significant benefits over existing options.
EXPLORE MORE HighlightsTo accelerate advanced breakthroughs of your projects, we offer broad range of platforms which enable our clients be free to tackle problems with cutting-edge technologies from different angles and in different methods.
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EXPLORE MORE HighlightsAll products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
The EPCAM gene provides instructions for making a protein known as epithelial cellular adhesion molecule (EpCAM). This protein is found in epithelial cells, which are the cells that line the surfaces and cavities of the body. The EpCAM protein is found spanning the membrane that surrounds epithelial cells, where it helps cells stick to one another (cell adhesion). In addition, the protein in the cell membrane can be cut at a specific location, releasing a piece called the intracellular domain (EpICD), which helps relay signals from outside the cell to the nucleus of the cell. EpICD travels to the nucleus and associates with other proteins, forming a group (complex) that regulates the activity of several genes that are involved in cell growth and division (proliferation), maturation (differentiation), and movement (migration), all of which are important processes for the proper development of cells and tissues.
Associated Disease
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| CAT | Product Name | Target Species | Antibody Clone | Antibody Host | Receptor Construction | Vector Type | Targeting Cell Type | CAR Vector Type | Inquiry & Datasheet |
| CAR-ZP3691 | Anti-EGP-2 (C2) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | C2 | Humanized | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3692 | Anti-EGP-2 (C2) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | C2 | Humanized | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3693 | Anti-EGP-2 (LD9) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | LD9 | Humanized | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3694 | Anti-EGP-2 (LD9) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | LD9 | Humanized | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3732 | Anti-EGP-2 (VU-1D9) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | VU-1D9 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3733 | Anti-EGP-2 (AUA1) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | AUA1 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3734 | Anti-EGP-2 (AUA1) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | AUA1 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3735 | Anti-EGP-2 (AT37F9) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | AT37F9 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3736 | Anti-EGP-2 (AT37F9) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | AT37F9 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3739 | Anti-EGP-2 (MOC-181) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | MOC-181 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3740 | Anti-EGP-2 (MOC-181) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | MOC-181 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3741 | Anti-EGP-2 (B8-4) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | B8-4 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3742 | Anti-EGP-2 (B8-4) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | B8-4 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3743 | Anti-EGP-2 (HEA-125) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | HEA-125 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3744 | Anti-EGP-2 (HEA-125) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | HEA-125 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3745 | Anti-EGP-2 (4A7) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 4A7 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3746 | Anti-EGP-2 (4A7) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | 4A7 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3747 | Anti-EGP-2 (7E11) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 7E11 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3748 | Anti-EGP-2 (7E11) h(41BB-CD3ζ) CAR, pCDCAR1 | Human | 7E11 | Mouse | scFv-41BB-CD3ζ | Lentiviral vector | T cell | ||
| CAR-ZP3749 | Anti-EGP-2 (1B7) h(CD28-CD3ζ) CAR, pCDCAR1 | Human | 1B7 | Mouse | scFv-CD28-CD3ζ | Lentiviral vector | T cell |
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NEW SOLUTION
CellRapeutics™ In Vivo Cell Engineering: One-stop in vivo T/B/NK cell and macrophage engineering services covering vectors construction to function verification.
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NOVEL TECHNOLOGY
Silence™ CAR-T Cell: A novel platform to enhance CAR-T cell immunotherapy by combining RNAi technology to suppress genes that may impede CAR functionality.
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Canine CAR-T Therapy Development: From early target discovery, CAR design and construction, cell culture, and transfection, to in vitro and in vivo function validation.
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