EpCAM

Epithelial cell adhesion molecule (EpCAM), also called DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation and differentiation. This protein can be used as a potential prognostic marker and as a potential target for immunotherapeutic strategies. EpCAM is associated with a lot of cancers including colon cancer, breast cancer, ovarian cancer, renal cancer (RCC), head and neck squamous cell carcinoma (HNSCC) and esophagus squamous cell carcinomas.

Associated Disease
Anti-EpCAM CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC181 T cell Third ~8kb Retroviral scFv-CD28-41BB-CD3ζ Human Inquiry
CAR-MZ151 T cell First M13-57 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-MZ152 T cell Second M13-57 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-MZ153 T cell Second M13-57 ~8kb Lentiviral scFv-41BB-CD3ζ Human Inquiry
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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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Tel: 44-207-097-1828

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