FRα(Folate receptor-alpha)

Folate receptor-alpha (FRα), also known as FOLR1, FBP, FOLR, FR1, is a glycosylphosphatidyl-inositol-linked protein encoded by FOLR1 gene. This receptor is a membrane-bound protein with high affinity for binding and transporting physiologic levels of folate into cells. Compare to normal cells, FRα is overexpressed on ovarian and several other epithelial malignancies including renal cancer, lung cancer and breast cancer. Therefore, FRα can be used as a target for imaging and therapy.

Associated Disease
Anti-FRα(Folate receptor-alpha) CAR Product list:
Catalog Targeting
Cell Type
Generation Antibody
Clone
Vector
Length
Vector
Type
Vector Design Antibody
Host
Data
sheet
Price
CAR-LC006 T cell Second C4 ~8kb Lentiviral scFv-CD27-CD3ζ Human Inquiry
CAR-LC040 T cell Second MOv19 ~8kb Lentiviral scFv-ICOS-CD3ζ Mouse Inquiry
CAR-LC164 T cell Second C4 ~8kb Lentiviral scFv-CD28-CD3ζ Human Inquiry
CAR-LC165 T cell First C4 ~8kb Lentiviral scFv-CD3ζ Human Inquiry
CAR-LC360 T cell Second MOv19 ~8kb Lentiviral scFv(MSLN)-CD3ζ/scFv(FRA)-CD28 Mouse Inquiry
CAR-MZ154 T cell First MOv19 ~8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-MZ155 T cell Second MOv19 ~8kb Lentiviral scFv-CD137-CD3ζ Mouse Inquiry
CAR-T-1-M313-2 T cell First MOv19 8kb Lentiviral scFv-CD28 Mouse Inquiry
CAR-T-1-M313-G T cell First MOv19 8kb Lentiviral scFv-FcεRIγ Mouse Inquiry
CAR-T-1-M313-Z T cell First MOv19 8kb Lentiviral scFv-CD3ζ Mouse Inquiry
CAR-T-2-M313-2G T cell Second MOv19 8kb Lentiviral scFv-CD28-FcεRIγ Mouse Inquiry
CAR-T-2-M313-2Z T cell Second MOv19 8kb Lentiviral scFv-CD28-CD3ζ Mouse Inquiry
CAR-T-2-M313-4G T cell Second MOv19 8kb Lentiviral scFv-CD4-FcεRIγ Mouse Inquiry
CAR-T-2-M313-4Z T cell Second MOv19 8kb Lentiviral scFv-CD4-CD3ζ Mouse Inquiry
CAR-T-2-M313-8Z T cell Second MOv19 8kb Lentiviral scFv-CD8-CD3ζ Mouse Inquiry
CAR-T-2-M313-BZ T cell Second MOv19 8kb Lentiviral scFv-41BB-CD3ζ Mouse Inquiry
CAR-T-2-M313-CZ T cell Second MOv19 8kb Lentiviral scFv-b2c-CD3ζ Mouse Inquiry
CAR-T-3-M313-2BZ T cell Third MOv19 8kb Lentiviral scFv-CD28-41BB-CD3ζ Mouse Inquiry
CAR-T-3-M313-2XZ T cell Third MOv19 8kb Lentiviral scFv-CD28-OX40-CD3ζ Mouse Inquiry
CONTACT US

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

Europe
Ringstrasse 4, 64401 Gross-Bieberau, Germany
Tel: 44-207-097-1828

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